Endocrine Abstracts

Background: Parathyroid carcinoma (PC) is rare, usually presenting with hyperparathyroidism and severe hypercalcemia. A standardized diagnostic, prognostic and therapeutic approach has not been provided yet and TNM staging algorithm is not universally accepted. Surgery is the first-choice treatment and is the only effective therapy to control hypercalcaemia. Chemo- or radio-therapy, local treatments or novel drugs should be reserved to selected cases.Cas...

Background: Overt hyperthyroidism can have a negative impact on pregnancy’s outcome, if not correctly treated. Furthermore anti thyroid treatment are burned by possible side effects.Objectives: We describe the experience of our center in the management of endogenous hyperthyroidism in pregnancy. evaluating the effects of the disease and treatments on fetal and maternal health.Methods: We observed 36 pregnancies (4 twins and 1 ...

Background: Endogenous and exogenous factors may cause biochemical interferences with thyroid function immunoassays. Interference can be caused by many mechanisms including heterophilic antibodies, drugs and rheumatoid factors. Moreover, assay-specific interference has been described, such as antithyroid hormone antibodies resulting in falsely elevated or lowered concentrations depending on the assay.Case Presentation: We describe a case of a 38-years ol...